# ClinicalTrials.gov API: Get clinical trial by NCT number or title

> Returns the full public record of a ClinicalTrials.gov study, looked up by NCT number or by title (closest registered title for ambiguous titles).

Unofficial. Not affiliated with or endorsed by ClinicalTrials.gov.

- Page: https://fous.com/methods/clinicaltrials.gov/get-trial
- Method: `clinicaltrials.gov/get_trial`, version 1
- Website: clinicaltrials.gov
- Returns: title, official title, purpose, status, phase, sponsor, dates, eligibility, arms, treatments, outcomes, locations, contacts
- Effect: read (it gets data and changes nothing)
- Sign-in: none needed
- Cost: 1 credit per completed run (1¢ with pay as you go); failed runs are free
- Verified: Nov 2, 2026

## Inputs

| Field | Type | Required | In the run below | Description |
|---|---|---|---|---|
| `trial` | string | yes | `"NCT04368728"` | The trial title or NCT trial number, for example NCT04368728. |

## Output

From a run on Oct 23, 2026, shortened. Its input:

```json
{
  "trial": "NCT04368728"
}
```

Its output:

```json
{
  "arms": [
    {
      "name": "10 µg dose, 18-55 years of age (2 doses)",
      "type": "Experimental",
      "treatments": [
        "Biological: BNT162b1",
        "Biological: BNT162b2"
      ],
      "description": null
    },
    {
      "name": "20 µg dose, 18-55 years of age (2 doses)",
      "type": "Experimental",
      "treatments": [
        "Biological: BNT162b1",
        "Biological: BNT162b2"
      ],
      "description": null
    },
    {
      "name": "30 µg dose, 18-55 years of age (2 doses)",
      "type": "Experimental",
      "treatments": [
        "Biological: BNT162b1",
        "Biological: BNT162b2"
      ],
      "description": null
    }
  ],
  "phase": "Phase 2 / Phase 3",
  "title": "Study to Describe the Safety, Tolerability, Immunogenicity, and Efficacy of RNA Vaccine Candidates Against COVID-19 in Healthy Individuals",
  "status": "Completed",
  "sponsor": "BioNTech SE",
  "age_range": "12 Years and older",
  "locations": [
    {
      "city": "Athens",
      "country": "United States",
      "facility": "North Alabama Research Center, LLC",
      "recruitment_status": null
    },
    {
      "city": "Birmingham",
      "country": "United States",
      "facility": "Birmingham Clinical Research Unit",
      "recruitment_status": null
    },
    {
      "city": "Huntsville",
      "country": "United States",
      "facility": "Medical Affiliated Research Center",
      "recruitment_status": null
    }
  ],
  "start_date": "2020-04-29",
  "treatments": [
    {
      "arms": [
        "10 µg dose, 18-55 years of age (2 doses)",
        "10 µg dose, 65-85 years of age (2 doses)",
        "100 µg dose, 18-55 years of age (2 doses)"
      ],
      "name": "BNT162b1",
      "type": "Biological",
      "description": "Intramuscular injection"
    },
    {
      "arms": [
        "10 µg dose, 18-55 years of age (2 doses)",
        "10 µg dose, 65-85 years of age (2 doses)",
        "20 µg dose, 18-55 years of age (2 doses)"
      ],
      "name": "BNT162b2",
      "type": "Biological",
      "description": "Intramuscular injection"
    },
    {
      "arms": [
        "Placebo, 18-55 years of age",
        "Placebo, 65-85 years of age",
        "Placebo, ≥12 years of age"
      ],
      "name": "Placebo",
      "type": "Other",
      "description": "Intramuscular injection"
    }
  ],
  "trial_link": "https://clinicaltrials.gov/study/NCT04368728",
  "trial_number": "NCT04368728",
  "official_title": "A PHASE 1/2/3, PLACEBO-CONTROLLED, RANDOMIZED, OBSERVER-BLIND, DOSE-FINDING STUDY TO EVALUATE THE SAFETY, TOLERABILITY, IMMUNOGENICITY, AND EFFICACY OF SARS-COV-2 RNA VACCINE CANDIDATES AGAINST COVID-19 IN HEALTHY INDIVIDUALS",
  "results_posted": true,
  "completion_date": "2023-02-10",
  "public_contacts": [],
  "purpose_summary": "This is a Phase 1/2/3, randomized, placebo-controlled, observer-blind, dose-finding, vaccine candidate-selection, and efficacy study in healthy individuals.\n\nThe study consists of 2 parts: Phase 1: to identify preferred vaccine candidate(s) and dose level(s); Phase 2/3: an expanded cohort and effica…",
  "primary_outcomes": [
    {
      "measure": "Percentage of Participants With Local Reactions Within 7 Days After Dose 1: Phase 1",
      "time_frame": "Within 7 days after Dose 1",
      "description": "Local reactions included redness, swelling and, pain at the injection site, recorded by participants in an electronic diary (e-diary). Redness and swelling were measured and recorded in measuring device units. 1 measuring device unit =0.5 centimeter (cm). Redness and swelling were graded as mild (gr…"
    },
    {
      "measure": "Percentage of Participants With Local Reactions Within 7 Days After Dose 2: Phase 1",
      "time_frame": "Within 7 days after Dose 2",
      "description": "Local reactions included redness, swelling and, pain at the injection site, recorded by participants in an e-diary. Redness and swelling were measured and recorded in measuring device units. 1 measuring device unit =0.5 cm. Redness and swelling were graded as mild (\\> 2.0 to 5.0 cm), moderate (\\> 5.…"
    },
    {
      "measure": "Percentage of Participants With Systemic Events Within 7 Days After Dose 1: Phase 1",
      "time_frame": "Within 7 days after Dose 1",
      "description": "Systemic events included fever, fatigue, headache, chills, vomiting, diarrhea, new or worsened muscle pain, new or worsened joint pain recorded by participants or parents/legal guardians of participants using e-diary. Fever=temperature \\>=38.0 deg C categorized as \\>=38.0 to 38.4, \\>38.4 to 38.9, \\>…"
    }
  ],
  "secondary_outcomes": [
    {
      "measure": "Geometric Mean Titers (GMTs) of Severe Acute Respiratory Syndrome Coronavirus 2 Neutralizing Titers: Phase 1",
      "time_frame": "7, 21 days after Dose 1; 7, 14 days and 1, 6 months after Dose 2",
      "description": "GMTs of severe acute respiratory syndrome coronavirus 2 neutralizing titers were reported in this outcome measure. SARS-CoV-2 neutralization assay - NT50 and SARS-CoV-2 neutralization assay - NT90 were evaluated and reported in this outcome measure."
    },
    {
      "measure": "Geometric Mean Concentrations (GMCs) of Severe Acute Respiratory Syndrome Coronavirus 2: S1-binding and RBD-binding IgG Level Assay: Phase 1",
      "time_frame": "7, 21 days after Dose 1; 7, 14 days and 1, 6 months after Dose 2",
      "description": "GMCs of severe acute respiratory syndrome coronavirus S1-binding and RBD-binding IgG level were reported in this outcome measure."
    },
    {
      "measure": "Geometric Mean Fold Rise (GMFR) of SARS-CoV-2 Neutralizing Titers: Phase 1",
      "time_frame": "7, 21 days after Dose 1; 7, 14 days and 1, 6 months after Dose 2",
      "description": "GMFR of SARS-CoV-2 neutralizing titers were reported in this outcome measure. HIV positive participants excluded."
    }
  ],
  "eligibility_criteria": "Inclusion Criteria:\n\n• Male or female participants between the ages of 18 and 55 years, inclusive, 65 and 85 years, inclusive, or ≥12 years, inclusive, at randomization (dependent upon study phase). For the boostability and protection-against-VOCs subset: Existing participants enrolled to receive a …",
  "number_of_participants": 46969
}
```

## Run it

From code, with a Fous API key in `FOUS_API_KEY`; the answer's `data` holds the output:

```bash
curl https://api.fous.com/v1/runs \
  -H "Authorization: Bearer $FOUS_API_KEY" \
  -H "Content-Type: application/json" \
  -d '{"method":"clinicaltrials.gov/get_trial","input":{"trial":"NCT04368728"}}'
```

From an AI agent connected to the Fous MCP server: its `run` with the same method and input. To connect one, give it `set up https://fous.com/SKILL.md`.

## Ask your agent

- Pull up the full record for NCT04368728, including eligibility criteria and study arms
- What are the primary outcomes and enrollment locations for the trial NCT03548935?
- Find the registered trial titled 'Efficacy of semaglutide in adults with type 2 diabetes' and tell me its sponsor and phase
- On ClinicalTrialsgov, I need the current recruitment status and contact details for NCT05123456
- Look up the study on the site whose official title mentions a 12-week mRNA vaccine booster and show its interventions and dates

## Input schema

```json
{
  "type": "object",
  "required": [
    "trial"
  ],
  "properties": {
    "trial": {
      "type": "string",
      "description": "The trial title or NCT trial number, for example NCT04368728."
    }
  }
}
```

## Output schema

```json
{
  "type": "object",
  "required": [
    "title",
    "official_title",
    "purpose_summary",
    "status",
    "phase",
    "sponsor",
    "start_date",
    "completion_date",
    "number_of_participants",
    "eligibility_criteria",
    "age_range",
    "arms",
    "treatments",
    "primary_outcomes",
    "secondary_outcomes",
    "locations",
    "public_contacts",
    "results_posted",
    "trial_number",
    "trial_link"
  ],
  "properties": {
    "arms": {
      "type": "array",
      "items": {
        "type": "object",
        "required": [
          "name",
          "type",
          "description",
          "treatments"
        ],
        "properties": {
          "name": {
            "type": [
              "string",
              "null"
            ]
          },
          "type": {
            "type": [
              "string",
              "null"
            ]
          },
          "treatments": {
            "type": "array",
            "items": {
              "type": "string"
            }
          },
          "description": {
            "type": [
              "string",
              "null"
            ]
          }
        },
        "additionalProperties": false
      }
    },
    "phase": {
      "type": [
        "string",
        "null"
      ]
    },
    "title": {
      "type": [
        "string",
        "null"
      ]
    },
    "status": {
      "type": [
        "string",
        "null"
      ]
    },
    "sponsor": {
      "type": [
        "string",
        "null"
      ]
    },
    "age_range": {
      "type": [
        "string",
        "null"
      ]
    },
    "locations": {
      "type": "array",
      "items": {
        "type": "object",
        "required": [
          "facility",
          "city",
          "country",
          "recruitment_status"
        ],
        "properties": {
          "city": {
            "type": [
              "string",
              "null"
            ]
          },
          "country": {
            "type": [
              "string",
              "null"
            ]
          },
          "facility": {
            "type": [
              "string",
              "null"
            ]
          },
          "recruitment_status": {
            "type": [
              "string",
              "null"
            ]
          }
        },
        "additionalProperties": false
      }
    },
    "start_date": {
      "type": [
        "string",
        "null"
      ],
      "format": "date"
    },
    "treatments": {
      "type": "array",
      "items": {
        "type": "object",
        "required": [
          "name",
          "type",
          "description",
          "arms"
        ],
        "properties": {
          "arms": {
            "type": "array",
            "items": {
              "type": "string"
            }
          },
          "name": {
            "type": [
              "string",
              "null"
            ]
          },
          "type": {
            "type": [
              "string",
              "null"
            ]
          },
          "description": {
            "type": [
              "string",
              "null"
            ]
          }
        },
        "additionalProperties": false
      }
    },
    "trial_link": {
      "type": "string"
    },
    "trial_number": {
      "type": "string"
    },
    "official_title": {
      "type": [
        "string",
        "null"
      ]
    },
    "results_posted": {
      "type": "boolean"
    },
    "completion_date": {
      "type": [
        "string",
        "null"
      ],
      "format": "date"
    },
    "public_contacts": {
      "type": "array",
      "items": {
        "type": "object",
        "required": [
          "name",
          "role",
          "phone",
          "email",
          "facility"
        ],
        "properties": {
          "name": {
            "type": [
              "string",
              "null"
            ]
          },
          "role": {
            "type": [
              "string",
              "null"
            ]
          },
          "email": {
            "type": [
              "string",
              "null"
            ]
          },
          "phone": {
            "type": [
              "string",
              "null"
            ]
          },
          "facility": {
            "type": [
              "string",
              "null"
            ]
          }
        },
        "additionalProperties": false
      }
    },
    "purpose_summary": {
      "type": [
        "string",
        "null"
      ]
    },
    "primary_outcomes": {
      "type": "array",
      "items": {
        "type": "object",
        "required": [
          "measure",
          "description",
          "time_frame"
        ],
        "properties": {
          "measure": {
            "type": [
              "string",
              "null"
            ]
          },
          "time_frame": {
            "type": [
              "string",
              "null"
            ]
          },
          "description": {
            "type": [
              "string",
              "null"
            ]
          }
        },
        "additionalProperties": false
      }
    },
    "secondary_outcomes": {
      "type": "array",
      "items": {
        "type": "object",
        "required": [
          "measure",
          "description",
          "time_frame"
        ],
        "properties": {
          "measure": {
            "type": [
              "string",
              "null"
            ]
          },
          "time_frame": {
            "type": [
              "string",
              "null"
            ]
          },
          "description": {
            "type": [
              "string",
              "null"
            ]
          }
        },
        "additionalProperties": false
      }
    },
    "eligibility_criteria": {
      "type": [
        "string",
        "null"
      ]
    },
    "number_of_participants": {
      "type": [
        "integer",
        "null"
      ]
    }
  },
  "additionalProperties": false
}
```

## See more

- [ClinicalTrials.gov API: Search clinical trials](https://fous.com/methods/clinicaltrials.gov/search-trials.md): Finds ClinicalTrials.gov studies for a condition or medicine. You can filter by location, distance, recruitment status and phase. With a location, results are ordered by distance to the closest eligible site.
- [ClinicalTrials.gov API: List company trials](https://fous.com/methods/clinicaltrials.gov/list-company-trials.md): Lists ClinicalTrials.gov studies run or funded by a sponsor, newest start date first, with optional phase, status and condition filters.
- [NIH API: Get PubMed article](https://fous.com/methods/pubmed.ncbi.nlm.nih.gov/get-article.md): Gets the full PubMed abstract and publication details for one article by title, PubMed link, or PubMed number (PMID). A title is searched in PubMed titles first and must closely match a found article. Some articles have no abstract or free full text.
- [NIH API: Search PubMed articles](https://fous.com/methods/pubmed.ncbi.nlm.nih.gov/search-articles.md): Finds PubMed medical and life-science articles by topic, with publication details and free full-text links when PubMed confirms them.
- [NIH API: Search grants](https://fous.com/methods/reporter.nih.gov/search-grants.md): Finds NIH research grants by topic, organisation, or researcher name. Searches the last five fiscal years by default.
- [NIH API: Search diagnosis codes](https://fous.com/methods/clinicaltables.nlm.nih.gov/search-diagnosis-codes.md): Finds ICD-10-CM diagnosis codes and official names from a plain-language condition description, retrying with simplified wording when the first search finds nothing.
- [Google API: Get patent details](https://fous.com/methods/patents.google.com/get-patent.md): Gets one public patent or published application by number, title, or Google Patents link, with claims, citations, family and classifications.
- [Grants.gov API: Search grant opportunities](https://fous.com/methods/grants.gov/search-grants.md): Finds U.S. federal grant opportunities by topic, agency, applicant type and status, with funding and eligibility details. Open results exclude opportunities whose closing date has passed.
- [All ClinicalTrials.gov methods](https://fous.com/methods/clinicaltrials.gov.md)
