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Medical research articles, article abstracts and publication details

PubMed searches medical and life-science articles by topic and retrieves one article’s abstract and publication details; abstracts and free full-text links may be unavailable.

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Article title, PubMed link, or PubMed number. Example: Effects of intermittent fasting on health, aging, and disease

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Issue
11
Pages
1491-1499
Title
Effects of Time-Restricted Eating on Weight Loss and Other Metabolic Parameters in Women and Men With Overweight and Obesity: The TREAT Randomized Clinical Trial.
Volume
180
Journal
JAMA internal medicine
Abstract
IMPORTANCE: The efficacy and safety of time-restricted eating have not been explored in large randomized clinical trials. OBJECTIVE: To determine the effect of 16:8-hour time-restricted eating on weight loss and metabolic risk markers. INTERVENTIONS: Participants were randomized such that the consistent meal timing (CMT) group was instructed to eat 3 structured meals per day, and the time-restricted eating (TRE) group was instructed to eat ad libitum from 12:00 pm until 8:00 pm and completely abstain from caloric intake from 8:00 pm until 12:00 pm the following day. DESIGN, SETTING, AND PARTICIPANTS: This 12-week randomized clinical trial including men and women aged 18 to 64 years with a body mass index (BMI, calculated as weight in kilograms divided by height in meters squared) of 27 to 43 was conducted on a custom mobile study application. Participants received a Bluetooth scale. Participants lived anywhere in the United States, with a subset of 50 participants living near San Francisco, California, who underwent in-person testing. MAIN OUTCOMES AND MEASURES: The primary outcome was weight loss. Secondary outcomes from the in-person cohort included changes in weight, fat mass, lean mass, fasting insulin, fasting glucose, hemoglobin A1c levels, estimated energy intake, total energy expenditure, and resting energy expenditure. RESULTS: Overall, 116 participants (mean [SD] age, 46.5 [10.5] years; 70 [60.3%] men) were included in the study. There was a significant decrease in weight in the TRE (-0.94 kg; 95% CI, -1.68 to -0.20; P = .01), but no significant change in the CMT group (-0.68 kg; 95% CI, -1.41 to 0.05, P = .07) or between groups (-0.26 kg; 95% CI, -1.30 to 0.78; P = .63). In the in-person cohort (n = 25 TRE, n = 25 CMT), there was a significant within-group decrease in weight in the TRE group (-1.70 kg; 95% CI, -2.56 to -0.83; P < .001). There was also a significant difference in appendicular lean mass index between groups (-0.16 kg/m2; 95% CI, -0.27 to -0.05; P = .005). There were no significant changes in any of the other secondary outcomes within or between groups. There were no differences in estimated energy intake between groups. CONCLUSIONS AND RELEVANCE: Time-restricted eating, in the absence of other interventions, is not more effective in weight loss than eating throughout the day. TRIAL REGISTRATION: ClinicalTrials.gov Identifiers: NCT03393195 and NCT03637855.
DOI Link
doi.org
Pubmed ID
32986097
Publication Date
2020-11-01
Free Full Text Link
pmc.ncbi.nlm.nih.gov
Conflict of Interest
Conflict of Interest Disclosures: Dr Lowe reported personal fees from Keyto outside the submitted work. Dr Vittinghoff reported personal fees from UCSF during the conduct of the study. Dr Heymsfield reported personal fees from Medifast Medical Advisory Board and personal fees from Tanita Medical Advisory Board outside the submitted work. Dr Weiss reported grants from NIH, grants from James Peter Read Foundation, nonfinancial support from Mocacare Inc, and nonfinancial support from IHealth labs during the conduct of the study; he also is a cofounder and equity stake holder of Keyto, Inc; and owns stock and was formerly on the board of Virta, Inc. No other disclosures were reported.
Authors
Authors
NameAffiliations
Dylan A Lowe
Cardiovascular Research Institute, University of California, San Francisco, San Francisco.
Nancy Wu
Cardiology Division, University of California, San Francisco, San Francisco., Center for Vulnerable Populations, University of California, San Francisco, San Francisco.
Linnea Rohdin-Bibby
Cardiology Division, University of California, San Francisco, San Francisco.
A Holliston Moore
Cardiology Division, University of California, San Francisco, San Francisco., Clovis Oncology Inc, Boulder, Colorado.
Nisa Kelly
University of Hawai'i Cancer Center, Honolulu.
Yong En Liu
University of Hawai'i Cancer Center, Honolulu.
Errol Philip
University of California School of Medicine, San Francisco.
Eric Vittinghoff
Cardiology Division, University of California, San Francisco, San Francisco.
Steven B Heymsfield
Pennington Biomedical Research Center, Baton Rouge, Louisiana.
Jeffrey E Olgin
Cardiology Division, University of California, San Francisco, San Francisco.
John A Shepherd
University of Hawai'i Cancer Center, Honolulu.
Ethan J Weiss
Cardiovascular Research Institute, University of California, San Francisco, San Francisco., Cardiology Division, University of California, San Francisco, San Francisco.
Keywords
None
Mesh Terms
  • Adult
  • Blood Glucose / metabolism
  • Body Mass Index
  • Caloric Restriction / methods
  • Diet Therapy / methods
  • Fasting / physiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Obesity / diet therapy
  • Obesity / metabolism
  • Obesity / therapy
  • Patient Compliance
  • Weight Loss
  • Young Adult
Publication Types
  • Journal Article
  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
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Search articles finds medical and life-science articles with publication details and available free full-text links, using a required topic.

Get article returns an article’s abstract and publication details, using its title, PubMed link, or PubMed number.

Built by Fous from pubmed.ncbi.nlm.nih.gov and eutils.ncbi.nlm.nih.gov and checked automatically; it last passed a check on Sep 28, 2026. Fous is not affiliated with PubMed.

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Get article

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Get the full PubMed abstract and publication details for one article by title, PubMed link, or PubMed number. Some articles do not have an abstract or free full text.

Uses eutils.ncbi.nlm.nih.gov.

What you provide

FieldTypeRequiredDescription
ArticlearticleTextRequiredArticle title, PubMed link, or PubMed number. Example: Effects of intermittent fasting on health, aging, and diseaseExample: https://pubmed.ncbi.nlm.nih.gov/32986097/

What you get

FieldTypeDescription
IssueissueTextExample: 11
PagespagesTextExample: 1491-1499
TitletitleTextExample: Effects of Time-Restricted Eating on Weight Loss and Other Metabolic…
VolumevolumeTextExample: 180
AuthorsauthorsList
Nameauthors[].nameTextExample: Dylan A Lowe
Affiliationsauthors[].affiliationsList
JournaljournalTextExample: JAMA internal medicine
AbstractabstractText
DOI Linkdoi_linkTextExample: https://doi.org/10.1001/jamainternmed.2020.4153
KeywordskeywordsList
Pubmed IDpubmed_idTextExample: 32986097
Mesh Termsmesh_termsList
Pubmed Linkpubmed_linkTextExample: https://pubmed.ncbi.nlm.nih.gov/32986097/
Publication Datepublication_dateTextExample: 2020-11-01
Publication Typespublication_typesList
Free Full Text Linkfree_full_text_linkTextExample: https://pmc.ncbi.nlm.nih.gov/articles/PMC7522780/
Conflict of Interestconflict_of_interestText

Example result

For Article: https://pubmed.ncbi.nlm.nih.gov/32986097/

JSON
{
  "issue": "11",
  "pages": "1491-1499",
  "title": "Effects of Time-Restricted Eating on Weight Loss and Other Metabolic Parameters in Women and Men With Overweight and Obesity: The TREAT Randomized Clinical Trial.",
  "volume": "180",
  "authors": [
    {
      "name": "Dylan A Lowe",
      "affiliations": [
        "Cardiovascular Research Institute, University of California, San Francisco, San Francisco."
      ]
    },
    {
      "name": "Nancy Wu",
      "affiliations": [
        "Cardiology Division, University of California, San Francisco, San Francisco.",
        "Center for Vulnerable Populations, University of California, San Francisco, San Francisco."
      ]
    },
    {
      "name": "Linnea Rohdin-Bibby",
      "affiliations": [
        "Cardiology Division, University of California, San Francisco, San Francisco."
      ]
    }
  ],
  "journal": "JAMA internal medicine",
  "abstract": "IMPORTANCE: The efficacy and safety of time-restricted eating have not been explored in large randomized clinical trials.\n\nOBJECTIVE: To determine the effect of 16:8-hour time-restricted eating on wei…",
  "doi_link": "https://doi.org/10.1001/jamainternmed.2020.4153",
  "keywords": [],
  "pubmed_id": "32986097",
  "mesh_terms": [
    "Adult",
    "Blood Glucose / metabolism",
    "Body Mass Index"
  ],
  "pubmed_link": "https://pubmed.ncbi.nlm.nih.gov/32986097/",
  "publication_date": "2020-11-01",
  "publication_types": [
    "Journal Article",
    "Randomized Controlled Trial",
    "Research Support, N.I.H., Extramural"
  ],
  "free_full_text_link": "https://pmc.ncbi.nlm.nih.gov/articles/PMC7522780/",
  "conflict_of_interest": "Conflict of Interest Disclosures: Dr Lowe reported personal fees from Keyto outside the submitted work. Dr Vittinghoff reported personal fees from UCSF during the conduct of the study. Dr Heymsfield r…"
}

Search articles

1 credit per run

Find PubMed medical and life-science articles by topic, with publication details and available free full-text links. Dates may be partial, and some records have no abstract or confirmed free full-text link.

Uses PubMed and ncbi.nlm.nih.gov.

What you provide

FieldTypeRequiredDescription
SortsortTextOptionalOrder by relevance or newest publication, for example newest.Example: Newest
QueryqueryTextRequiredTopic in plain words, for example intermittent fasting blood pressure.Example: intermittent fasting blood pressure
End Yearend_yearNumberOptionalLast publication year, for example 2024.Example: 2024
Start Yearstart_yearNumberOptionalFirst publication year, for example 2020.Example: 2022
Max Resultsmax_resultsNumberOptionalMaximum number of articles to return, for example 20 (up to 100).Example: 5
Article Typearticle_typeTextOptionalArticle type, for example systematic_review.Example: Systematic review
Free Full Text Onlyfree_full_text_onlyYes or noOptionalOnly include articles PubMed marks as free full text, for example true.Example: Yes

What you get

FieldTypeDescription
ArticlesarticlesListMatching articles in the requested order.
DOIarticles[].doiTextDigital object identifier, when available.Example: 10.3390/nu16203533
Titlearticles[].titleTextArticle title.Example: Is Fasting Superior to Continuous Caloric Restriction for Weight Loss and…
Authorsarticles[].authorsTextFirst three authors, followed by et al. if there are more.Example: Víctor Siles-Guerrero, Jose M Romero-Márquez, Rosa Natalia García-Pérez, et al.
Journalarticles[].journalTextJournal name, when available.Example: Nutrients
Pubmed IDarticles[].pubmed_idTextPubMed identifier.Example: 39458528
Pubmed Linkarticles[].pubmed_linkTextPubMed article page.Example: https://pubmed.ncbi.nlm.nih.gov/39458528/
Article Typearticles[].article_typeTextPubMed publication type.Example: Meta-Analysis
Abstract Excerptarticles[].abstract_excerptTextFirst 300 characters of the abstract, when available.Example: BACKGROUND: fasting-based strategies (FBS) and continuous caloric restriction…
Publication Datearticles[].publication_dateTextPublication date, as YYYY-MM-DD, YYYY-MM, or YYYY when only part is known.Example: 2024-10-18
Free Full Text Linkarticles[].free_full_text_linkTextA confirmed free full-text page, when available.Example: https://pmc.ncbi.nlm.nih.gov/articles/PMC11510157/

Example result

For Sort: Newest, Query: intermittent fasting blood pressure, End Year: 2024, Start Year: 2022, Max Results: 5, Article Type: Systematic review, Free Full Text Only: Yes

JSON
{
  "articles": [
    {
      "doi": "10.3390/nu16203533",
      "title": "Is Fasting Superior to Continuous Caloric Restriction for Weight Loss and Metabolic Outcomes in Obese Adults? A Systematic Review and Meta-Analysis of Randomized Clinical Trials.",
      "authors": "Víctor Siles-Guerrero, Jose M Romero-Márquez, Rosa Natalia García-Pérez, et al.",
      "journal": "Nutrients",
      "pubmed_id": "39458528",
      "pubmed_link": "https://pubmed.ncbi.nlm.nih.gov/39458528/",
      "article_type": "Meta-Analysis",
      "abstract_excerpt": "BACKGROUND: fasting-based strategies (FBS) and continuous caloric restriction (CCR) are popular methods for weight loss and improving metabolic health. FBS alternates between eating and fasting period…",
      "publication_date": "2024-10-18",
      "free_full_text_link": "https://pmc.ncbi.nlm.nih.gov/articles/PMC11510157/"
    },
    {
      "doi": "10.1016/j.cjca.2024.02.004",
      "title": "Risks and Benefits of Intermittent Fasting for the Aging Cardiovascular System.",
      "authors": "Mualla Ozcan, Mahmoud Abdellatif, Ali Javaheri, et al.",
      "journal": "The Canadian journal of cardiology",
      "pubmed_id": "38354947",
      "pubmed_link": "https://pubmed.ncbi.nlm.nih.gov/38354947/",
      "article_type": "Systematic Review",
      "abstract_excerpt": "Population aging and the associated increase in cardiovascular disease rates pose serious threats to global public health. Different forms of fasting have become an increasingly attractive strategy to…",
      "publication_date": "2024-02-12",
      "free_full_text_link": "https://linkinghub.elsevier.com/retrieve/pii/S0828-282X(24)00092-8"
    }
  ]
}

For developers

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cURL
# First set your key: export FOUS_API_KEY='YOUR_FOUS_API_KEY'
: "${FOUS_API_KEY:?Set FOUS_API_KEY before running this example}"

curl 'https://api.fous.com/v1/query' \
  --fail-with-body --silent --show-error --max-time 120 \
  -H "Authorization: Bearer $FOUS_API_KEY" \
  -H 'Content-Type: application/json' \
  --data-raw '{
  "api": "@pubmed",
  "visibility": "public",
  "operation": "get_article",
  "version": 1,
  "input": {
    "article": "https://pubmed.ncbi.nlm.nih.gov/32986097/"
  },
  "response": {
    "format": "json"
  }
}'

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